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KMID : 0882420180930030285
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Korean Journal of Medicine
2018 Volume.93 No. 3 p.285 ~ p.290
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A Hepatic Lymphoma Mimicking Multiple Liver Metastases or an Intrahepatic Cholangiocarcinoma
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Oh Joo-Hyun
Choi Moon-Seok
Shin Dong-Hyun
Kim Seok-Jin
Kang Tae-Wook
Ko Young-Hyeh
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Abstract
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A primary hepatic lymphoma (PHL) is a rare malignancy; misdiagnosis and mistreatment are very common. We report the case of a 56-year-old female who presented with a 2-week history of upper abdominal pain. She exhibited no risk factors for hepatocellular carcinoma (HCC) and her serum tumor marker levels were normal. A computed tomography scan and gadolinium-enhanced magnetic resonance imaging of the liver revealed multiple liver masses, suggestive of multiple liver and lung metastases or an intrahepatic cholangiocarcinoma with lung metastasis. A diagnosis of PHL (a diffuse large B cell lymphoma) was confirmed by biopsy followed by immunohistochemistry. This case emphasizes that a PHL must be considered in the differential diagnosis of space-occupying liver lesions in patients with no risk factors for HCC and normal levels of serum tumor markers. It is notable that neither B cell lymphoma symptoms nor an elevated lactate dehydrogenase level were apparent in this case. We thus report a case of PHL mimicking multiple liver metastases or an intrahepatic cholangiocarcinoma, and we review the literature.
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KEYWORD
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Liver neoplasm, Lymphoma, Non-hodgkin, Lymphoma, Large B-Cell, Diffuse, Primary hepatic lymphoma
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